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In the version of this article initially published, the total AMPKα immunoblot shown in Extended Data Fig. 8b, which presents a doxycycline concentration course, was inadvertently duplicated from Fig. 4f, which presents a doxycycline time course. The published Supplementary Information contains separate uncropped AMPKα immunoblots for these experiments in Supplementary Figs. 7 and 17. Extended Data Fig. 8b has now been corrected using the appropriate blot documented in Supplementary Fig. 17. Its legend has also been corrected by replacing “Time course” with “Concentration course” and “total AMPK” with “total AMPKα”.
An incorrect β-actin loading-control image was also inadvertently used in Fig. 4f during figure assembly. It has been replaced with the correct blot from that experiment, as documented in Supplementary Fig. 7.
The bottom row of Fig. 2f and Extended Data Fig. 3q derive from the same 79-day endpoint of the same orthotopic experiment. In Fig. 2f, these bioluminescence images were incorrectly labelled “76 days”; the label has been corrected to “79 days”.
Due to the age of the article, the figures cannot be updated directly. For transparency, the original and corrected panels are provided as Supplementary Information accompanying this amendment. These errors were introduced during figure preparation and labelling and do not affect the results or conclusions of the study.
Supplementary information is available in the online version of this amendment.
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These authors contributed equally: Prasenjit Dey and Joelle Baddour
Authors and Affiliations
Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
Prasenjit Dey, Wen-Ting Liao, Zangdao Lan, Alina Chen, Di Zhao, Y. Alan Wang & Ronald A. DePinho
Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
Prasenjit Dey, Chia Chin Wu, Tony Gutschner, Edward Chang, Giannicola Genovese, Andrea Viale, Giulio Draetta & Y. Alan Wang
Joelle Baddour, Abhinav Achreja, Lifeng Yang, Jiyoon Lee & Deepak Nagrath
Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
Florian Muller & Nikunj Satani
Department of Pathology, Division of Pathology/Lab Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
Department of Surgical Oncology, Division of Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
Yaan Kang & Jason Fleming
Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
Edward Chang & Giulio Draetta
Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
Sheikh Ahmed Bin Zayed Al Nahyan Center for Pancreatic Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
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Correspondence to Y. Alan Wang, Deepak Nagrath or Ronald A. DePinho.
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Dey, P., Baddour, J., Muller, F. et al. Author Correction: Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer. Nature (2026). https://doi.org/10.1038/s41586-026-11134-x
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DOIhttps://doi.org/10.1038/s41586-026-11134-x
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